Brain scans show that girls were especially affected by the loss of social interaction.
The pandemic was supposed to be a temporary disruption, but for many teenagers, it caused changes that may never fully reverse. A study from the University of Washington reveals that the Covid lockdowns, with their school closures, canceled activities, and isolation, accelerated the aging of teen brains by as much as four years. The findings, published in Proceedings of the National Academy of Sciences, add weight to growing concerns about how such disruptions to normal life have fueled a surge in mental health struggles, particularly among adolescents.
The study tracked the brain development of 160 teens from Seattle, using MRIs starting in 2018. The participants—both boys and girls, ranging in age from 9 to 19—showed significant thinning of the cortex, the outer layer of the brain responsible for higher cognitive functions like reasoning and decision-making. This premature brain aging, while not definitively linked to the pandemic, suggests that the isolation, stress, and loss of social interaction during the lockdowns may have exacerbated underlying mental health issues.
In fact, a similar study by Stanford University in 2022 compared the disruptions of the pandemic to childhood trauma, noting that the stresses of Covid—particularly the isolation—were not unlike the effects of violence, neglect, or family dysfunction. Dr. Patricia Kuhl, the lead researcher at the University of Washington, emphasized that for adolescents, whose emotional and behavioral development is already in full swing, this period of forced solitude was especially damaging.
Teen mental health was deteriorating even before the pandemic, but since 2021, reports from the Centers for Disease Control and Prevention (CDC) have highlighted unprecedented levels of anxiety, depression, and suicidal thoughts among teens. A CDC survey released in August found that 53% of high school girls still report persistent sadness, a stark reminder of the emotional toll Covid continues to exact.
The adolescent years are crucial for developing social skills and emotional resilience, points out Dr. Jonathan Posner, a psychiatrist at Duke University. Teens rely heavily on peer interactions to shape their emotional lives, and the loss of these interactions during the pandemic has left many struggling to catch up. While the brain’s cortex continues to shrink throughout life, the study revealed that the lockdowns caused far more thinning than would be expected over such a short period of time.
For girls, this thinning was particularly pronounced, with changes occurring across 30 brain regions. In boys, the thinning was more localized, affecting just two areas involved in memory and perception. Kuhl suggests that the stronger social bonds girls form may have made them more vulnerable to the emotional fallout of isolation, whereas boys often rely on physical activity and sports to cope.
While this research paints a sobering picture, it also offers hope. Dr. Posner remains optimistic about teens’ resilience. “Fortunately, kids are really resilient,” he says. “We can help them get back on track.” However, he cautions that the pandemic's impact should not be underestimated. “This was not just a brief inconvenience. It had a significant impact on growth and development,” he warns.
The study also points to the long-term effects of this brain aging. While it’s not yet clear whether these changes will increase the risk of disorders like ADHD, depression, or even neurodegenerative diseases like Alzheimer’s, the possibility looms large. The brain, after all, doesn’t regrow its cortex, and the accelerated thinning seen during the pandemic may leave lasting marks.
Seattle mother Karin Zaugg Black saw firsthand how her children struggled with remote learning. Her daughter Delia, then 14, missed the social connection that is so vital to teen life. “When she reflects back, she says it was really hard. She felt like she had no friends, and that was really difficult,” Black explains. However, Delia, now a senior in high school, has regained much of her social confidence. Experts agree that while the effects of the pandemic may not be entirely permanent, the emotional scars will take time to heal.
The study’s results underscore a stark reality: the isolation caused by the pandemic was not merely a disruption—it was a trauma that left a lasting imprint on adolescent development. The road to recovery will be long, but with time, support, and attention to mental health, teens can still regain what was lost.
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